This is a tool for visualizing the gene expression response of rodent models and cultured cells upon exposure to chemical purturbations.

Use the menus at the top of the screen to select the chemical and experimental conditions of interest.

The 1000 most perturbed genes are summarized by the Reactome pathways that contain them. Reactome is a hierarchical ontology describing cellular physiology.

Only the Reactome pathways significantly overrepresented by the altered genes for the chemical perturbation are shown.

TG-GATEs data are available here. Hamner legacy data are published here